What are the substantial risk criteria for postexposure prophylaxis (PEP) following nonoccupational HIV infection exposure?

Updated: Apr 18, 2019
  • Author: R Chris Rathbun, PharmD, BCPS (AQ-ID), AAHIVP; Chief Editor: John Bartlett, MD  more...
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Substantial risk criteria include the following:

  • Site of exposure - Vagina, rectum, eye, mouth, or other mucous membrane, nonintact skin, or percutaneous contact

  • Infectious material - Blood, semen, vaginal secretions, rectal secretions, breast milk, or any body fluid that is visibly contaminated with blood

  • Source status - Known HIV infection in the source

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