What is used as secondary prophylaxis against MRSA infection in patients with HIV infection?

Updated: Mar 09, 2021
  • Author: Justin R Hofmann, MD; Chief Editor: John Bartlett, MD  more...
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For recurrent methicillin-resistant S aureus (MRSA) infection, the recommendation is mupirocin 2% nasal ointment to each nostril twice daily for 5 days if colonization is documented. Long-term efficacy is uncertain, and resistance may develop. Germicidal soaps have been recommended for perineal colonization, but little evidence suggests efficacy. Hygienic measures should be emphasized for this epidemic problem.

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