What is used as secondary prophylaxis against herpes simplex infection in patients with HIV infection?

Updated: Mar 09, 2021
  • Author: Justin R Hofmann, MD; Chief Editor: John Bartlett, MD  more...
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For recurrent herpes simplex infection, valacyclovir 500 mg PO BID or acyclovir 400 mg PO daily is recommended as long-term suppression (AI recommendation). The ongoing need for continued suppression should be evaluated yearly as the CD4 cell count rises with ART.

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