What is used as secondary prophylaxis against toxoplasmosis in patients with HIV infection?

Updated: Mar 09, 2021
  • Author: Justin R Hofmann, MD; Chief Editor: John Bartlett, MD  more...
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Answer

Answer

For toxoplasmosis, the following is recommended: sulfadiazine 500 to 1000 mg orally 4 times daily plus pyrimethamine 25 to 50 mg orally daily and leucovorin 10 to 25 mg orally daily (AI recommendation) until the CD4 count exceeds 200 cells/μL for 6 months (AIII recommendation). An additional agent must be added to prevent PCP.


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