How were the CDC/NIH/IDSA guidelines for preventing opportunistic infections in patients with HIV structured?

Updated: Mar 09, 2021
  • Author: Justin R Hofmann, MD; Chief Editor: John Bartlett, MD  more...
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Answer

Answer

The recommendations below use evidence-based criteria as published by the joint CDC/NIH/IDSA that summarize the strength of the recommendation and quality of the evidence [1] :

Strength of recommendation is as follows:

A: Strong recommendation for the statement

B: Moderate recommendation for the statement

C: Optional recommendation for the statement

Quality of evidence for the recommendation is as follows:

I: One or more randomized trials with clinical outcomes and/or validated laboratory endpoints

II: One or more well-designed, nonrandomized trials or observational cohort studies with long-term clinical outcomes

III: Expert opinion


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