What is the role of opportunistic infection prevention in the treatment of HIV infection?

Updated: Mar 09, 2021
  • Author: Justin R Hofmann, MD; Chief Editor: John Bartlett, MD  more...
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Answer

Answer

Prevention of opportunistic infections (OI) in patients with HIV has since significantly reduced morbidity and mortality in these patients. HIV-related infections and malignancies escalate in frequency and severity as the absolute CD4 T cell count falls toward 200 cells/μL and below. This risk is more prominent in patients with lower CD4 counts as well as in patients with a longer time spent with more severe immunosuppression; however, it is also seen more severely in patients not on ART. [2]  Patients should be aware of their CD4 count and their risk for specific infections and should begin ART.

 


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