What are the histologic findings in aortic regurgitation (AR)?

Updated: Nov 19, 2018
  • Author: Stanley S Wang, JD, MD, MPH; Chief Editor: Terrence X O'Brien, MD, MS, FACC  more...
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Answer

Histologic valvular findings in patients with AR depend on the AR’s cause. Patients with congenital abnormalities can usually be easily characterized noninvasively or grossly at the time of surgery or during pathologic inspection.

Aortic root dilation may be present in up to 25% of patients with AR due to bicuspid valve. Many patients with a bicuspid aortic valve have concurrent aortopathy, including connective tissue and cellular abnormalities, that predisposes these individuals to aortic dilation, aneurysm, and dissection. [8]


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