What are the demographics of aortic regurgitation (AR)?

Updated: Nov 19, 2018
  • Author: Stanley S Wang, JD, MD, MPH; Chief Editor: Terrence X O'Brien, MD, MS, FACC  more...
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The prevalence of AR appears to be similar across racial populations in the United States, although internationally there is significant variation in the prevalence of predisposing conditions, such as rheumatic heart disease. [21]

AR is seen more commonly in men than in women. In the cohort from the Framingham study, AR was found in 13% of men and 8.5% of women. [20] The greater prevalence of AR in men may reflect, in part, the preponderance of underlying conditions, such as Marfan syndrome [22] or bicuspid aortic valve, in males. [23]

Chronic aortic regurgitation often begins in patients when they are in their late 50s and is documented most frequently in patients older than 80 years. In general, the prevalence and severity of AR increase with age, although severe chronic AR is uncommon before age 70 years. [20] However, there are many exceptions to this observation. Patients with bicuspid aortic valve and, especially, those with Marfan syndrome tend to present much earlier. [22, 23]

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