What are the mortality rates for cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)?

Updated: Oct 09, 2018
  • Author: Reza Behrouz, DO, FACP; Chief Editor: Helmi L Lutsep, MD  more...
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Answer

The exact mortality rate in patients with CADASIL is unknown. The age at onset for stroke is 45-50 years. The mean age at death has been reported to be 61 years after a mean disease duration of approximately 23 years. [6] Men tend to die earlier than women. [7] Fewer than half of patients older than age 60 could walk without assistance. [5] Close to 80% of patients are completely dependent immediately before death. [7]


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