How are acute episodes of porphyria treated?

Updated: Aug 31, 2020
  • Author: Brenda Chiang, DO; Chief Editor: Emmanuel C Besa, MD  more...
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Treatment of acute episodes addresses symptoms and includes parenteral narcotics for pain. Hemin (plasma-derived intravenous heme) is the definitive treatment and mainstay of management.

Avoidance of sunlight is the key in treating cutaneous porphyrias. Afamelanotide, an α-melanocyte–stimulating hormone analogue, may permit increased duration of sun exposure in patients with erythropoietic protoporphyria.


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