What is the Clark classification of melanoma?

Updated: Jun 28, 2021
  • Author: Jonathan B Heistein, MD; Chief Editor: Gregory Gary Caputy, MD, PhD, FICS  more...
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See the list below:

  • Level I - Involves only epidermis (in situ melanoma); no invasion

  • Level II - Invades papillary dermis but not papillary-reticular dermal interface

  • Level III - Invades and expands papillary dermis up to the interface with, but not into, reticular dermis

  • Level IV - Invades reticular dermis but not into subcutaneous tissue

  • Level V - Invades into subcutaneous tissue

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