What is the role of biopsy in the workup of fibrosarcoma?

Updated: Dec 03, 2018
  • Author: Ian D Dickey, MD, FRCSC, LMCC; Chief Editor: Omohodion (Odion) Binitie, MD  more...
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Ultimately, the diagnosis of fibrosarcoma is made with tissue obtained from a biopsy. Biopsy should be thought of as the first step toward treatment, rather than the last step in diagnosis. Biopsy should always follow a full radiographic workup.

Biopsy is best performed by the treating surgeon because that physician will be responsible for any final tumor resection and reconstruction. In addition, it is best performed at a center where a team approach is used in treating these rare tumors. At such centers, groups of oncologists, pathologists, radiologists, and surgeons, all with a specific interest in these problems, often are present. This broad pool of experience contributes greatly to the interpretation of tests and to the ultimate treatment outcome.

Any biopsy performed must include an adequate volume of tissue. In centers with expert interpretation, core needle biopsy (CNB) may be acceptable.

The biopsy must be performed in a way that avoids compromising any planned surgical excision or reconstruction. It must not contaminate significant neurovascular structures.

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