Answer
Plain radiographs of the involved anatomic region are needed to evaluate for primary or secondary involvement of bone. (See the image below.) Typically, an osteolytic area of destruction with a permeative or moth-eaten appearance is present. Little periosteal reaction or reactive sclerosis is depicted.
Although fibrosarcoma of bone can arise anywhere, it is found most commonly about the knee and femur. The radiograph here shows a typical appearance of a lesion in bone.
For bony lesions, plain radiographs often greatly assist in diagnosis and the determination of location, size, and local extent of involvement. For soft-tissue masses, size often can be estimated, any bone involvement can be seen, and intralesional content (matrix) can sometimes be determined.
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Media Gallery
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Although fibrosarcoma of bone can arise anywhere, it is found most commonly about the knee and femur. The radiograph here shows a typical appearance of a lesion in bone.
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Most pathologists describe the histologic picture of fibrosarcoma as a herringbone pattern. It is an interlacing pattern of sheets of spindle-shaped fibroblasts in a collagen background. This pattern is very distinctive and usually confirms the diagnosis of fibrosarcoma.
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