What is the prevalence of fibrosarcoma?

Updated: Dec 03, 2018
  • Author: Ian D Dickey, MD, FRCSC, LMCC; Chief Editor: Omohodion (Odion) Binitie, MD  more...
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Answer

Fibrosarcoma represents only about 10% of musculoskeletal sarcomas and fewer than 5% of all primary tumors of bone. It can be diagnosed in patients of any age, but it is diagnosed more commonly in patients in the fourth decade of life. It is usually located in the lower extremities, especially the femur and tibia.

Fibrosarcoma of the soft tissues usually affects a wider age spectrum of patients than fibrosarcoma of the bone does, with an age range of 35-55 years. It often arises in the soft tissues of the thigh and the posterior knee. It is generally a large, painless mass deep to fascia and has an ill-defined margin.

An infantile form (in children < 10 years) of fibrosarcoma exists. Unlike fibrosarcoma in adults, it has an excellent prognosis—even in the face of metastatic disease at presentation—when treated with a combination of neoadjuvant and adjuvant chemotherapy and resection. [7, 8, 9, 10]

Fibrosarcoma of bone occurs slightly more commonly in men than in women. No known racial predilection exists.


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