Which medications in the drug class Glucagonlike Peptide-1 Agonists are used in the treatment of Obesity?

Updated: Jun 09, 2021
  • Author: Osama Hamdy, MD, PhD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
  • Print
Answer

Glucagonlike Peptide-1 Agonists

Glucagonlike peptide-1 (GLP-1) agonists have shown to promote weight loss in patients with or without type 2 diabetes mellitus. GLP-1 is a physiologic regulator of appetite and calorie intake, and the GLP-1 receptor is present in several areas of the brain involved in appetite regulation. 

Liraglutide (Saxenda)

Liraglutide is indicated for chronic weight management as an adjunct to diet and exercise in adults with a BMI of ≥30 (obese) or adults with a BMI of ≥27 (overweight) who have at least one weight-related condition (eg, hypertension, type 2 diabetes, dyslipidemia). It is administered as a daily SC injection.

Semaglutide (Wegovy)

Semaglutide is indicated for chronic weight management as an adjunct to diet and exercise in adults with a BMI of ≥30 (obese) or adults with a BMI of ≥27 (overweight) who have at least one weight-related condition (eg, hypertension, type 2 diabetes, dyslipidemia). It is administered as a once-weekly SC injection. 


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!