Are most medications for obesity approved for short-term or long-term use?

Updated: Jun 09, 2021
  • Author: Osama Hamdy, MD, PhD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Most medications for obesity are approved for short-term use only. Available literature indicates that their utility is severely limited when they are given in this fashion. Obesity is a chronic medical condition, and as with similar chronic conditions (eg, diabetes, hypertension), after therapeutic agents are stopped, the relapse rate is high. The need for any pharmaceutical regimen to be combined with a sustained exercise, dietary adjustment, and behavioral-change regimen to sustain weight loss further complicates the successful management of obesity.

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