How much weight loss is associated with clinically meaningful health benefits in patients with obesity?

Updated: Jun 09, 2021
  • Author: Osama Hamdy, MD, PhD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Available data suggest that a loss of approximately 10% of body weight in persons who are obese (body mass index [BMI] < 40 kg/m2) is associated with substantial health benefits regarding obesity-related comorbidities. [117] However, according to guidelines released by the American College of Cardiology (ACC), the American Heart Association (AHA), and The Obesity Society (TOS) in 2013, clinically meaningful health improvements can even be seen with weight loss in the range of 2%-5%. [111, 112]

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