Which factors modulate the morbidity and mortality associated with obesity?

Updated: Jun 09, 2021
  • Author: Osama Hamdy, MD, PhD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Factors that modulate the morbidity and mortality associated with obesity include the following:

  • Age of onset and duration of obesity

  • Severity of obesity

  • Amount of central adiposity

  • Comorbidities

  • Gender

  • level of cardiorespiratory fitness

  • Race

A study by Jung et al found a correlation between abdominal obesity and high-volume benign prostatic hyperplasia (BPH), ie, a prostate volume of 40 mL or greater. The report, which involved 571 participants, also found a positive association between serum leptin levels and high-volume BPH and a negative association between serum adiponectin and high-volume BPH. [103]

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