Which medications in the drug class Antidepressants, SNRIs are used in the treatment of Foot Drop?

Updated: Mar 23, 2020
  • Author: James W Pritchett, MD; Chief Editor: Vinod K Panchbhavi, MD, FACS  more...
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Antidepressants, SNRIs

Pharmacologic agents with reuptake inhibition of serotonin and norepinephrine such as duloxetine (Cymbalta) may be helpful in a variety of mood and anxiety disorders. Duloxetine is also cleared for use for chronic musculoskeletal pain, anxiety, and depression. It can be used for neuropathy and has also been used for fibromyalgia.

Duloxetine (Cymbalta, Irenka)

Duloxetine is a potent inhibitor of neuronal serotonin and norepinephrine uptake, and antidepressant action is thought to be due to serotonergic and noradrenergic potentiation in the central nervous system.

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