Which clinical history findings are characteristic of acute retinal necrosis in HIV infection?

Updated: Jul 21, 2021
  • Author: Luca Rosignoli, MD; Chief Editor: Andrew A Dahl, MD, FACS  more...
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Patients with ARN usually present with eye pain associated with decreased visual acuity, floaters, and history of recent HSV or VZV infection. In early disease, funduscopic examination often reveals small, necrotic yellowish lesions in the periphery, which rapidly spread into a larger confluent white area, most often involving the entire peripheral retina, and then progress toward the posterior pole.

In about 36% of cases, the contralateral eye is also involved. Associated anterior uveitis, retinal vasculitis, episcleritis, scleritis, or retinal detachment may be present.

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