How is ocular tuberculosis in HIV infection treated?

Updated: Jul 21, 2021
  • Author: Luca Rosignoli, MD; Chief Editor: Andrew A Dahl, MD, FACS  more...
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Answer

Answer

Patients should be given isoniazid (INH) 300 mg orally daily, rifampin 600 mg orally daily, and pyrazinamide 25-35 mg/kg orally daily for 2 months; then,  INH and rifampin should be continued for an additional 7 months. Drug resistance is most common with streptomycin and INH; however, this may be minimized using multiple bactericidal antituberculous drugs. For patients with pulmonary cavitary lesions, respiratory culture can help detect resistant strains.

Pyridoxine 25 mg orally daily usually is added to the regimen to prevent peripheral neuritis.


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