What is the role of conjunctival microvasculopathy in HIV infection?

Updated: Jul 21, 2021
  • Author: Luca Rosignoli, MD; Chief Editor: Andrew A Dahl, MD, FACS  more...
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Answer

Answer

Several conjunctival microvascular changes occur in as many as 70-80% of patients who are HIV positive. These changes include segmental vascular dilation and narrowing, microaneurysm formation, and appearance of comma-shaped vascular fragments.

The specific etiology of the microvascular changes is not known; however, increased plasma viscosity and immune-complex deposition are believed to be contributory. Direct infection of the conjunctival vascular endothelium by HIV has been suggested as a possible cause.


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