Which medications in the drug class Oral contraceptives are used in the treatment of Hirsutism?

Updated: May 01, 2020
  • Author: George T Griffing, MD; Chief Editor: Michel E Rivlin, MD  more...
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Answer

Oral contraceptives

OCs inhibit ovarian androgen production and are probably the first choice for young women with hirsutism who do not want to become pregnant. OCs are inexpensive, and they promote regular uterine bleeding. OCs can be used in combination with antiandrogens or other agents. They have a significant failure rate in hirsutism for several reasons. Low-dose OCs and progestin-only minipills fail to suppress ovulation in as many as 50% of women. Ovarian function continues at a variable rate, and ovarian androgens continue to be produced. Second, the progestins in OCs are attenuated derivatives of testosterone and have variable degrees of androgenic activity in women. The degree depends on the type of progestin and, more importantly, on individual susceptibility.

Ethinyl Estradiol, drospirenone, and levomefolate (Beyaz)

Combination of estrogen and progestin that suppresses ovarian production of androgens.

Ethinyl estradiol and norethindrone (Estrostep Fe)

Combination of estrogen and progestin that suppresses ovarian production of androgens.

Ethinyl estradiol and norgestimate (Ortho Tri-Cyclen)

Combination of estrogen and progestin that suppresses ovarian production of androgens.

Ethinyl Estradiol and Drospirenone (Yaz)

Combination of estrogen and progestin that suppresses ovarian production of androgens.

Norethindrone acetate and ethinyl estradiol (Ortho-Novum, Nortrel, Cyclafem)

Combination of estrogen and progestin that suppresses ovarian production of androgens.


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