What is iris melanoma?

Updated: Jul 13, 2021
  • Author: Buraa Kubaisi, MD, FICO, MRCS(Edin); Chief Editor: Michael Taravella, MD  more...
  • Print
Answer

Answer

Iris nevi and melanomas are the most common primary tumors of the iris, with an incidence ranging from 50-70% of all iris tumors; of these, 10-24% may be melanomas. Melanomas arise from malignant proliferation of the neuroectodermally derived iris stromal melanocytes, which replaces the normal iris stromal architecture. While melanoma is the most common primary malignancy of the iris, it comprises only 3%-10% of all uveal melanomas. [1]  Considerable controversy exists regarding the histopathologic classification and the malignant potential of iris melanomas.

See The Case of the Middle-Aged Woman with Sudden Unilateral Vision Loss, a Critical Images slideshow, to help identify and treat malignant intraocular tumors.

See Ciliary Body Melanoma, Choroidal Melanoma, and Conjunctival Melanoma for complete information on these topics.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!