What is the role of lab tests in the workup of ciliary body melanoma?

Updated: Mar 03, 2020
  • Author: Enrique Garcia-Valenzuela, MD, PhD; Chief Editor: Andrew A Dahl, MD, FACS  more...
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Because the most common site of metastasis is the liver, obtain liver enzyme levels in any patient with ciliary body melanoma.

The most sensitive hepatic function tests are serum levels of gamma-glutamyl transpeptidase, lactic dehydrogenase, and glutamic-oxaloacetic transaminase.

If any of these serum levels are abnormal, ultrasonographic and computed tomography (CT) scan studies of the liver are indicated. Unfortunately, both imaging modalities have low sensitivity for micrometastasis (smaller than 1-2 cm in diameter).

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