What causes ciliary body melanoma?

Updated: Mar 03, 2020
  • Author: Enrique Garcia-Valenzuela, MD, PhD; Chief Editor: Andrew A Dahl, MD, FACS  more...
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Answer

Answer

Primary ciliary body melanoma arises from melanocytes in the uveal tract. Although uveal melanomas may grow de novo, most develop from a preexisting melanocytic nevus. Three distinct cell types are recognized in uveal melanomas: spindle A, spindle B, and epithelioid.

Epithelioid cells are associated with more aggressive behavior and carry a poorer prognosis for the patient's survival.


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