What are the treatment options for newborns with gonococcal infection bacterial conjunctivitis (pink eye)?

Updated: Jan 03, 2019
  • Author: Karen K Yeung, OD, FAAO; Chief Editor: Andrew A Dahl, MD, FACS  more...
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N gonorrhoeae infection of the newborn also requires systemic treatment of the neonate, the mother, and at-risk contacts. The neonate may be treated with intravenous aqueous penicillin G 100 units/kg/d in 4 divided doses for 1 week. The mother and at-risk contacts may be treated with a single dose of intramuscular ceftriaxone 125 mg followed by oral doxycycline 100 mg twice daily for 7 days. Strict daily attention to the peripheral cornea, conjunctival scarring, and membrane formation allows timely surgical action: corneal cyanoacrylate glue for corneal melts and glass rod lysis of the conjunctival membranes destined to become symblepharons without intervention. Amniotic membrane therapy may also be beneficial in more extreme cases.

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