What is peripheral anterior synechiae caused by hyphema?

Updated: Jan 18, 2019
  • Author: David L Nash, MD; Chief Editor: Andrew A Dahl, MD, FACS  more...
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Peripheral anterior synechiae occur frequently in medically treated patients in whom the hyphema has remained in the anterior chamber for a prolonged period, typically 9 or more days. The pathogenesis of peripheral anterior synechiae may be due to a prolonged iritis associated with the initial trauma and/or chemical iritis resulting from blood in the anterior chamber. Alternately, the clot in the chamber angle may subsequently organize, producing trabecular meshwork fibrosis that closes the angle. Both mechanisms are likely to be involved. [6, 11]

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