What is the role of increased temperature in the development of euthyroid sick syndrome?

Updated: Aug 28, 2020
  • Author: Serhat Aytug, MD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Induction of increased temperature in patients with primary hypothyroidism results in demonstrable decreases in serum TSH, and thyroid hormone secretion may be less in summer than winter. Acute exposure to heat decreases serum T3 and causes reciprocal elevation of rT3. Both total T3 and free T3 commonly are decreased in patients who are hyperpyrexic.

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