Which lab and imaging studies are included in the workup of first adult seizure?

Updated: Nov 30, 2017
  • Author: Eissa Ibrahim AlEissa, MD, MBBS; Chief Editor: Selim R Benbadis, MD  more...
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Metabolic screening for uremia, hypoglycemia, drug intoxications, and electrolyte disorders should be conducted for patients with first seizure who present to the emergency department. [36] Perform other laboratory investigations as indicated for specific clinical situations.

Neuroimaging should be performed, because discovery of an epileptogenic lesion can have an impact on the diagnosis, prognosis, and treatment of new-onset seizures. Chadwick and Smith concluded that plausible arguments may be made for obtaining routine early computed tomography (CT) scanning and reserving magnetic resonance imaging (MRI) for patients with epilepsy whose seizures are not controlled by antiepileptic drugs. [37]

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