What are the causes of first seizure in adults?

Updated: Nov 30, 2017
  • Author: Eissa Ibrahim AlEissa, MD, MBBS; Chief Editor: Selim R Benbadis, MD  more...
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Answer

Causes of epilepsy include the following:

  • Prenatal, perinatal, or postnatal complications of pregnancy and delivery

  • Febrile seizure, which must be differentiated between a complex febrile seizure and a simple febrile seizure

  • Cerebrovascular disease, such as cerebral infarction, cerebral hemorrhage, and venous thrombosis

  • Head trauma, which is more significant when it occurs with loss of consciousness lasting longer than 30 minutes, posttraumatic amnesia lasting longer than 30 minutes, focal neurologic findings, or neuroimaging findings suggesting a structural brain injury

  • Central nervous system (CNS) infections, such as meningitis or encephalitis

  • Neurodegenerative diseases

  • Autoimmune disease

  • Brain neoplasm

  • Genetic diseases

  • Drug intoxication, drug withdrawal, or alcohol withdrawal

  • Metabolic medical disorders, such as uremia, hypoglycemia, hyponatremia, and hypocalcemia


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