What is included in the long-term monitoring of patients with absence seizures?

Updated: Sep 25, 2018
  • Author: Scott Segan, MD; Chief Editor: Selim R Benbadis, MD  more...
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Answer

Answer

Children with absence seizures should be monitored closely during titration or crossover of AEDs. The dose of the medication should be increased weekly until seizures are controlled or adverse effects develop.

The aim in therapy is to control seizures completely with the minimum required amount of medication to minimize adverse effects.

The therapeutic effect of valproic acid for absence seizures may lag several weeks behind reaching a therapeutic level. [51]

Liver function test, amylase and/or lipase, and complete blood cell (CBC) count results should be monitored during drug treatment to watch for adverse reactions.

Drug levels should be monitored to ensure treatment compliance and to watch for toxic levels in patients who are too young or too developmentally disabled to articulate subjective adverse effects.


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