When is urine ketone testing indicated in type 1 diabetes mellitus (DM)?

Updated: Oct 08, 2021
  • Author: Romesh Khardori, MD, PhD, FACP; Chief Editor: George T Griffing, MD  more...
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Instruct patients with type 1 DM in the method of testing for urine ketones with commercially available reagent strips. Advise patients to test for urine ketones whenever they develop any of the following:

  • Symptoms of a cold, flu, or other intercurrent illness

  • Nausea, vomiting, or abdominal pain

  • Polyuria

  • An unexpectedly high plasma glucose level on self-monitoring

  • Persistent, rapid, and marked fluctuation in the degree of hyperglycemia

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