What is the pathophysiology of primary pediatric craniosynostosis?

Updated: Dec 04, 2018
  • Author: Raj D Sheth, MD; Chief Editor: George I Jallo, MD  more...
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Answer

When 1 or more sutures fuse prematurely, skull growth can be restricted perpendicular to the suture. If multiple sutures fuse while the brain is still increasing in size, intracranial pressure can increase.

  • Scaphocephaly - Early fusion of the sagittal suture

  • Anterior plagiocephaly - Early fusion of 1 coronal suture

  • Brachycephaly - Early bilateral coronal suture fusion

  • Posterior plagiocephaly - Early closure of 1 lambdoid suture

  • Trigonocephaly - Early fusion of the metopic suture

    Frontal view showing a fused and ridged metopic su Frontal view showing a fused and ridged metopic suture on 3-dimensional CT.

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