What is the role of imaging studies in the workup of Kennedy disease (KD)?

Updated: Sep 30, 2019
  • Author: Paul E Barkhaus, MD, FAAN, FAANEM; Chief Editor: Nicholas Lorenzo, MD, MHA, CPE  more...
  • Print
Answer

Patients with KD tend to be middle aged or elderly, and they may have common neurologic conditions, such as spondylosis.

If cervical spondylosis is a consideration, or if marked asymmetry in muscle weakness is noted on follow-up of a patient with KD, imaging of the cervical spine is indicated.

MRI of the brain is indicated if clinical symptoms or endocrinologic testing suggest microadenoma.

Hamano et al reported MRI studies of the leg muscle in patients with KD and amyotrophic lateral sclerosis. [69] In contrast to patients with amyotrophic lateral sclerosis who showed atrophy, patients with KD showed associated high-signal intensity with atrophy consistent with fatty degeneration. This was seen in both proximal as well as distal muscles.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!