What is the role of needle EMG in the workup of primary lateral sclerosis (PLS)?

Updated: Sep 06, 2019
  • Author: Carmel Armon, MD, MSc, MHS; Chief Editor: Nicholas Lorenzo, MD, MHCM, CPE, FAAPL  more...
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Motor and sensory nerve conduction studies should be normal.

Needle EMG helps to distinguish primary lateral sclerosis (PLS) from ALS by identifying, in ALS, electrophysiologic evidence of widespread lower motor neuron involvement. The changes in PLS are minimal or absent.

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