Which age groups have the highest prevalence of primary lateral sclerosis (PLS)?

Updated: Sep 06, 2019
  • Author: Carmel Armon, MD, MSc, MHS; Chief Editor: Nicholas Lorenzo, MD, MHCM, CPE, FAAPL  more...
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A series of 43 patients reported a mean age of onset of 54.62 ± 10.9 years, with a range of 33-74 years. [4] This is similar to the age of onset range of 35-66 years with a median of 50.5 years reported earlier from the same center. [2]

Onset in a patient as young as 20 years was reported by Younger et al. [1]

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