What is the role of antiviral therapy in the treatment of aseptic meningitis?

Updated: Jul 17, 2018
  • Author: Tarakad S Ramachandran, MBBS, MBA, MPH, FAAN, FACP, FAHA, FRCP, FRCPC, FRS, LRCP, MRCP, MRCS; Chief Editor: Niranjan N Singh, MBBS, MD, DM, FAHS, FAANEM  more...
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Effective antiviral therapy is available against HSV-1, varicella, and cytomegalovirus. In immunosuppressed patients, long-term therapy may be necessary.

Acyclovir is recommended for immunocompetent hosts with HSV-2 meningitis and a primary genital herpes infection. Valacyclovir and foscarnet are alternative antiviral agents.

In patients with Mollaret meningitis, acyclovir (intravenous or oral) or valacyclovir (oral only) are worthy of consideration for both therapy and prophylaxis.

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