How is cytomegalovirus (CMV) encephalitis treated in patients with HIV infection?

Updated: Jan 08, 2020
  • Author: Regina Krel, MD; Chief Editor: Niranjan N Singh, MBBS, MD, DM, FAHS, FAANEM  more...
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Prompt initiation of antiviral drugs is essential for treatment of cytomegalovirus (CMV) encephalitis. [6] These agents inhibit viral replication by competing with deoxyguanosine triphosphate for viral DNA polymerase, inhibiting DNA synthesis. Medical support is required in cooperation with the primary care physician and an infectious diseases specialist.

Because the clinical presentation, cerebrospinal fluid (CSF) studies, and imaging studies may not provide a definitive diagnosis, a high level of suspicion is necessary to avoid a delay in proper therapy. Delayed diagnosis and treatment can lead to death.

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