What is the role of T SPECT and FDG PET scans in the evaluation of CNS complications in HIV infection?

Updated: Apr 12, 2018
  • Author: Regina Krel, MD; Chief Editor: Niranjan N Singh, MBBS, MD, DM, FAHS, FAANEM  more...
  • Print
Answer

Answer

If imaging shows one or more focal mass lesions without impending herniation, additional studies are warranted. When available, thallium-201 single-photon emission computed tomography (201 T SPECT) or 18-fluorodeoxyglucose positron emission tomography (18 FDG-PET) scan in conjunction with polymerase chain reaction (PCR) studies of the cerebrospinal fluid (CSF) for Epstein-Barr virus can provide strong evidence that a mass lesion represents a lymphoma. This may reduce the need for a stereotactic biopsy.

When these studies cannot be conducted, toxoplasmosis serology in conjunction with imaging results will determine how to proceed.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!