How is failure to empty managed in neurologic disease?

Updated: Aug 08, 2019
  • Author: Frances M Dyro, MD; Chief Editor: Robert A Egan, MD  more...
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Failure to empty occurs in the presence of inadequate detrusor contraction or excessive outflow resistance. Drugs that stimulate bladder contraction include parasympathomimetics, such as carbachol and bethanechol; the latter is more specific for the muscarinic receptors of the bladder. Drugs that act on the urethra to decrease outflow resistance include alpha-adrenoceptor antagonists, such as phenoxybenzamine and prazosin.

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