What is the role of 2D time-of-flight (TOF) MRA in acute stroke imaging?

Updated: Dec 09, 2020
  • Author: Souvik Sen, MD, MPH, MS, FAHA; Chief Editor: Helmi L Lutsep, MD  more...
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Two-dimensional (2D) TOF MRA also depends on the relative contrast between flowing blood and stationary tissue; it provides better images than 3D TOF in slow-flow regions. 2D TOF images correlate well with carotid angiography images in depicting cervical bifurcation disease. Their disadvantages, however, are the significant artifacts (eg, stepladder) that often occur, which may obscure vessel details, and the longer scanning time.

The modified TOF MRA technique, which uses multiple overlapping thin slab acquisitions (MOTSA), combines the advantages of 2D and 3D TOF techniques. It is very helpful in demonstrating severe stenosis, although the degree of stenosis might be slightly overestimated.

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