How is posterior reversible encephalopathy syndrome (PRES) distinguished from other CNS complications of systemic lupus erythematosus (SLE)?

Updated: May 04, 2021
  • Author: Pradeep C Bollu, MD; Chief Editor: Niranjan N Singh, MBBS, MD, DM, FAHS, FAANEM  more...
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Answer

Posterior reversible encephalopathy syndrome (PRES) has been described in SLE. Patients are generally on immunosuppressive drugs, have had episodes of relative hypertension, and have renal involvement. Magnetic resonance image (MRI) findings are characteristic, involving the occipital lobes in particular, which differentiates PRES from other central nervous system (CNS) complications of SLE. Clinical and radiographic resolution of abnormalities within 1-4 weeks is typically seen. In spite of this, patients with PRES might present with dramatic signs and symptoms. [13]


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