What is the Sunderland classification of nerve injuries?

Updated: Jun 08, 2018
  • Author: Charles F Guardia, III, MD; Chief Editor: Nicholas Lorenzo, MD, MHA, CPE  more...
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Sunderland’s classification specifies five degrees of nerve damage. [63] The first degree corresponds to neurapraxia in Seddon’s schema; the second corresponds to axonotmesis; and the third, fourth, and fifth correspond to increasingly severe levels of neurotmesis. In a Sunderland third-degree injury, axons and Schwann sheaths are disrupted within intact nerve fascicles. In a fourth-degree injury, the perineurium surrounding the fascicles is damaged, as is the endoneurium. In a fifth-degree injury, the nerve trunk is severed.

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