What causes differences in normal beta activity on EEG?

Updated: Oct 09, 2019
  • Author: Selim R Benbadis, MD; Chief Editor: Helmi L Lutsep, MD  more...
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In healthy individuals, beta activity commonly can be mildly different (< 35%) in amplitude between the 2 hemispheres, which may be caused by differences in skull thickness. Definite focal, regional, or hemispheric difference (at least 50%) in amplitude may be significant and may suggest either skull defect (side with higher amplitude) or a structural lesion (side with lower amplitude). [7] The amount and voltage of beta activity is enhanced by commonly used sedative medications (benzodiazepines, barbiturates).

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