What causes focal neurologic abnormalities on neonatal EEG?

Updated: Oct 03, 2019
  • Author: Rosalia C Silvestri-Hobson, MD; Chief Editor: Selim R Benbadis, MD  more...
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The following conditions may cause focal neurologic abnormalities: trauma, primary subarachnoid hemorrhage, intraventricular hemorrhage (IVH), intraparenchymal hemorrhage, and cerebral infarction. EEG abnormalities include an interhemispheric amplitude asymmetry pattern that is mainly seen with intraparenchymal hemorrhage or with a prenatal or postnatal ischemic insult. A wider criterion (>50%) is usually applied to preterm (PT) infants in whom significant hemispheric voltage alteration has been found to strongly correlate with contralateral hemiparesis. In 1984, Challamel reported that transient hemispheric asymmetries were a normal variant in infants with no CNS-related ailments who later resumed fully developed normal EEG patterns. [6, 7]

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