How is mild cognitive impairment (MCI) treated?

Updated: Apr 22, 2019
  • Author: Sonal Mehta, MD; Chief Editor: Jasvinder Chawla, MD, MBA  more...
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Although no established treatment exists for MCI, donepezil delays the progression to AD in MCI patients with depression without affecting their depressive symptoms, and some evidence suggests that cognitive interventions may have a positive effect. [4] Cholinesterase inhibitors have not been found to delay the onset of AD or dementia in MCI. [5]

Identify and monitor patients with MCI, because of their increased risk for AD (and, to a lesser extent, other dementing conditions). In addition, to the extent possible, correct any sensory and motor manifestations that compound their cognitive symptoms.

Diet and activity may have some positive effects in patients with MCI. The risk of developing MCI is lower in individuals who consume a Mediterranean diet, [6] and interactive, mentally challenging activities as well as moderate exercise have the potential to be helpful in MCI. [7]

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