What are the phase 2 symptoms of erythema infectiosum (fifth disease)?

Updated: Mar 06, 2020
  • Author: Glenn L Zellman, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

This phase occurs 1-4 days later and is characterized by an erythematous maculopapular rash on proximal extremities (usually arms and extensor surfaces) and trunk, which fades into a classic lacelike reticular pattern as confluent areas clear. [4] The palms and soles usually are spared, and pruritus is rare. (See the image below.)

Pathognomonic reticulated, lacy-appearing eruption Pathognomonic reticulated, lacy-appearing eruption of fifth disease.

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