What is the mortality and morbidity associated of congenital erythema infectiosum (fifth disease)?

Updated: Mar 06, 2020
  • Author: Glenn L Zellman, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

PV-B19 can cross the placenta during pregnancy and have a direct cytotoxic effect on fetal RBCs. [34] Infection may lead to the following:

  • Severe anemia

  • Congestive heart failure

  • Hydrops fetalis - PV-B19 is responsible for 10-15% of cases

  • Intrauterine death (miscarriage or stillborn) - In 3-10% of mothers who are infected


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