Is foscarnet effective in the treatment of chickenpox (varicella) in immunocompromised patients?

Updated: Aug 31, 2020
  • Author: Anthony J Papadopoulos, MD; Chief Editor: Dirk M Elston, MD  more...
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Foscarnet, an inorganic pyrophosphate analogue that acts as a selective inhibitor of viral deoxyribonucleic acid polymerases and reverse transcriptases, is a potentially efficacious drug in patients with acyclovir-resistant VZV strains. Optimal dosage, duration of therapy, and efficacy in primary varicella infection need further investigation. Treatment of primary varicella in these populations is difficult and necessitates an integrated team approach. [30]

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